Ab-origin

Temporary site for Ab-origin
Supplementary Materials: Ab-origin: An enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies Xiaojing Wang, Di Wu, Siyuan Zheng, Jing Sun, Lin Tao, Y.X. Li, Z.W. Cao Software An implementation of Ab-origin(version 1.6, uploaded at 2008.7.25) is found here. Additional files Additional file 1: S-Figure1: Length distribution of V-to-J region for simulated and real sequences Additional file 2 : S-Figure2: Simulation flowchart of antibody maturation process Additional file 3 : S-Table1: Results of IGHD identification among five existing tools from four sets of antibody heavy chain sequences Additional file 4 : S-Table2: Results of IGHD identification from Ab-origin with scores higher than 38. Additional file 5 : Simulation data set for testing Ab-origin accuracy and comparing with other tools. The random500.fasta was used in the initial evaluation in the Result part 3 ; the random1000.fasta was used in the further validation in the Result part 4 in the main text.

Temporary site for Ab-origin

Supplementary Materials: Ab-origin: An enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies

Xiaojing Wang, Di Wu, Siyuan Zheng, Jing Sun, Lin Tao, Y.X. Li, Z.W. Cao

Software

An implementation of Ab-origin(version 1.6, uploaded at 2008.7.25) is found here.

Additional files

Additional file 1: S-Figure1: Length distribution of V-to-J region for simulated and real sequences

Additional file 2 : S-Figure2: Simulation flowchart of antibody maturation process

Additional file 3 : S-Table1: Results of IGHD identification among five existing tools from four sets of antibody heavy chain sequences

Additional file 4 : S-Table2: Results of IGHD identification from Ab-origin with scores higher than 38.

Additional file 5 : Simulation data set for testing Ab-origin accuracy and comparing with other tools. The random500.fasta was used in the initial evaluation in the Result part 3 ; the random1000.fasta was used in the further validation in the Result part 4 in the main text.